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Review
. 2021 Mar 19;10(3):584.
doi: 10.3390/plants10030584.

Ethnobotanical Research and Compilation of the Medicinal Uses in Spain and the Active Principles of Chiliadenus glutinosus (L.) Fourr. for the Scientific Validation of Its Therapeutic Properties

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Review

Ethnobotanical Research and Compilation of the Medicinal Uses in Spain and the Active Principles of Chiliadenus glutinosus (L.) Fourr. for the Scientific Validation of Its Therapeutic Properties

Nadia Las Heras Etayo et al. Plants (Basel). .

Abstract

The species Chiliadenus glutinosus (L.) Fourr. has a large number of therapeutic uses reported in the traditional Spanish medicine. The growing interest in preserving the ethnopharmacological knowledge related to the botanical diversity existing in Spain and the interest in achieving scientific validation of the therapeutic properties of medicinal species has led to the development of this study. To do it, all the known medicinal uses of Ch. glutinosus in Spain were compiled, then an exhaustive bibliographic research on its chemical composition was carried out, and finally, an in silico validation of the bioactive phytochemicals present in a higher proportion in the essential oil of Ch. glutinosus: camphor, borneol, lucinone, glutinone, quercetin, kutdtriol, and kaempferol; in an attempt to justify the reported traditional uses of the species. It was found that much of the traditional medicinal uses of Ch. glutinosus, along with the biological activity of its phytochemicals, are supported by scientific evidence. The results place this species in a prominent position to initiate possible lines of research to develop new, more effective drugs and improve therapies to treat conditions and diseases that affect the different organic systems of the human being.

Keywords: Chiliadenus glutinosus; Spanish folk medicine; bioactive phytochemicals; ethnopharmacological; human body organic systems; in silico modeling.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Distribution map of the species Chiliadenus glutinosus (L.) Fourr. (left) and detail in Spain produced in the ArcGis software from data obtained in GBIF [27,28], corrected according the last revision of the Flora Iberica [7].
Figure 2
Figure 2
Flowering top of Chiliadenus glutinosus used in folk medicine and detail of the mature inflorescences. Photograph was taken in the town of Arnedillo (La Rioja).
Figure 3
Figure 3
Chemical structure in a two-dimensional format of the main compounds present in Chiliadenus glutinosus. Images obtained from NCBI [62,63,64,65,66,67,68].

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References

    1. Pardo de Santayana M., Morales R. Consideraciones sobre el género Jasonia (Compositae, Inuleae). Sistemática y usos. Acta Bot. Malacit. 2004;29:221–232. doi: 10.24310/abm.v29i0.7232. - DOI
    1. Gómiz García F., Morales Valverde R. Acerca de Jasonia hesperia Maire & Wilczek (Asteraceae) y las especies norteafricanas de este género. Acta Bot. Malacit. 2006;31:81–87. doi: 10.24310/abm.v31i31.7122. - DOI
    1. Guillén Bas A., Ferrer-Gallego P.P., Roselló Gimeno R., Gómez Navarro J., Laguna Lumbreras E., Peris J.B. Jasonia glutinosa subsp. congesta subsp. nov. (Compositae, Inuleae) Fl. Montiber. 2013;55:76–80. doi: 10.13140/RG.2.2.25344.79363. - DOI
    1. Lanfranco S., Lanfranco E., Westermeier R., Zammit M.-A., Mifsud M.-A., Xiberras J. The vascular flora of the Maltese Islands. In: Consell Insular de Menorca, editor. Islands and Plants: Preservation and Understanding of Flora on Mediterranean Islands. 1st ed. Institut Menorquí d’Estudis; Menorca, Spain: 2013. pp. 261–268.
    1. Kew Gardens. Missouri Botanical Garden The Plant List, a Working List of All Plant Species. [(accessed on 8 May 2020)]; Available online: http://www.theplantlist.org/

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