Serum IP-10 and IL-7 levels are associated with disease severity of coronavirus disease 2019

Cytokine. 2021 Jun:142:155500. doi: 10.1016/j.cyto.2021.155500. Epub 2021 Mar 19.

Abstract

We quantified the serum levels of 34 cytokines/chemokines in 30 patients with SARS-CoV-2 infection. Elevated levels of IP-10 and IL-7 were detected in the acute and convalescent stages of the infection and were highly associated with disease severity.

Keywords: COVID-19; Chemokine; Cytokine; Immune response; SARS-CoV-2.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 / blood*
  • Chemokine CXCL10 / blood*
  • Female
  • Humans
  • Interleukin-7 / blood*
  • Male
  • Middle Aged
  • SARS-CoV-2 / metabolism*
  • Severity of Illness Index*

Substances

  • CXCL10 protein, human
  • Chemokine CXCL10
  • Interleukin-7