A Diagnostic Score for Acute Small Bowel Obstruction

Anticancer Res. 2021 Apr;41(4):1959-1970. doi: 10.21873/anticanres.14963.

Abstract

Background/aim: The diagnosis of acute small bowel obstruction (ASBO) may be difficult and the decision to operate is based on clinical findings. So far, the diagnostic scores (DSs) for ASBO detection have been rarely evaluated.

Patients and methods: A cohort of 1,333 acute abdominal pain (AAP) patients with 54 ASBO patients, were included in the study. The most significant diagnostic findings (in multivariate logistic regression analysis) were used to construct DS formulas for ASBO diagnosis with location of pain at diagnosis (LP+) and without location of pain at diagnosis (LP-). Meta-analytical techniques were used to calculate the summary sensitivity (Se) and specificity (Sp) estimates for each data sets (history-taking, findings, and DS formulas).

Results: In SROC analysis, the AUC values for i) clinical history-taking, ii) diagnostic findings and tests, iii) DSLP- and iv) DSLP+ were as follows: i) AUC=0.638 (95%CI=0.600-0.676); ii) AUC=0.694 (95%CI=0.630-0.724), iii) AUC=0.962 (95%CI=0.940-0.986), and for iv) AUC=0.971 (95%CI=0.952-0.988). In roccomp analysis for the AUC values, the differences are significant as follows: between i) and ii) p=0.312; between i) and iii) p<0.0001; between i) and iv) p<0.0001; between ii) and iii) p<0.0001; between ii) and iv) p<0.0001; and between iii) and iv) p=0.317.

Conclusion: The present study is the first to provide data that the DS could be used for clinical diagnosis of ASBO without radiological or laboratory analyses, to reach a high diagnostic accuracy in AAP patients.

Keywords: Acute small bowel obstruction; HSROC; ROC; diagnostic accuracy; diagnostic score.

Publication types

  • Meta-Analysis

MeSH terms

  • Abdomen, Acute / diagnosis*
  • Abdomen, Acute / etiology
  • Abdomen, Acute / pathology
  • Abdominal Pain / diagnosis
  • Abdominal Pain / etiology
  • Abdominal Pain / pathology
  • Acute Disease
  • Area Under Curve
  • Cohort Studies
  • Datasets as Topic
  • Diagnosis, Differential
  • Diagnostic Techniques, Digestive System*
  • Humans
  • Intestinal Obstruction / complications
  • Intestinal Obstruction / diagnosis*
  • Intestinal Obstruction / pathology
  • Intestine, Small / pathology*
  • Medical History Taking
  • Predictive Value of Tests
  • Reproducibility of Results
  • Research Design
  • Sensitivity and Specificity