Abstract
Because of failure to fully respond to an initial intraarticular injection of dysprosium 165-ferric hydroxide macroaggregates, 17 patients with seropositive rheumatoid arthritis underwent repeat radiation synovectomy using this agent. Of the 13 patients who were evaluated 1 year later, 54% (7 knees) had good results, 31% (4 knees) had fair results, and 15% (2 knees) had poor results. The initial lack of significant benefit from radiation synovectomy did not appear to preclude a favorable response to a second injection.
MeSH terms
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Adult
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Aged
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Arthritis, Rheumatoid / physiopathology
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Arthritis, Rheumatoid / radiotherapy*
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Dysprosium / administration & dosage
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Dysprosium / therapeutic use*
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Evaluation Studies as Topic
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Ferric Compounds / administration & dosage
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Ferric Compounds / therapeutic use*
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Follow-Up Studies
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Humans
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Injections, Intra-Articular
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Knee Joint*
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Middle Aged
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Pain
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Radioisotopes / administration & dosage
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Radioisotopes / therapeutic use*
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Recurrence
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Synovial Membrane*
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Veins
Substances
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Ferric Compounds
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Radioisotopes
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Dysprosium
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ferric hydroxide