Elevated 68Ga-FAPI Activity in Splenic Hemangioma and Pneumonia

Clin Nucl Med. 2021 Aug 1;46(8):694-696. doi: 10.1097/RLU.0000000000003638.


A 59-year-old woman with newly diagnosed pulmonary nodules underwent both 18F-FDG and 68Ga-FAPI PET/CT. Both studies showed similarly increased uptake in pneumonia. However, only 68Ga-FAPI PET/CT showed increased uptake in splenic hemangioma, whereas FDG uptake in the splenic lesion is low. Our case illustrates that splenic hemangioma can also reveal increased FAPI activity.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Fluorodeoxyglucose F18 / metabolism
  • Hemangioma / diagnostic imaging
  • Hemangioma / metabolism*
  • Humans
  • Middle Aged
  • Pneumonia / diagnostic imaging
  • Pneumonia / metabolism*
  • Positron Emission Tomography Computed Tomography
  • Quinolines / metabolism*
  • Splenic Neoplasms / diagnostic imaging
  • Splenic Neoplasms / metabolism*


  • 68Ga-FAPI
  • Quinolines
  • Fluorodeoxyglucose F18