Fluid Stewardship of Maintenance Intravenous Fluids

J Pharm Pract. 2022 Oct;35(5):769-782. doi: 10.1177/08971900211008261. Epub 2021 Apr 8.

Abstract

Despite the frequent use of maintenance intravenous fluids (mIVF) in critically ill patients, limited guidance is available. Notably, fluid overload secondary to mIVF mismanagement is associated with significant adverse patient outcomes. The Four Rights (right drug, right dose, right duration, right patient) construct of fluid stewardship has been proposed for the safe evaluation and use of fluids. The purpose of this evidence-based review is to offer practical insights for the clinician regarding mIVF selection, dosing, and duration in line with the Four Rights of Fluid Stewardship.

Keywords: acute kidney injury; critical care; drug induced kidney injury; fluid therapy; maintenance fluid; stewardship.

Publication types

  • Review

MeSH terms

  • Critical Illness* / therapy
  • Fluid Therapy* / adverse effects
  • Humans