Effects of the COVID pandemic on pregnancy outcomes

Best Pract Res Clin Obstet Gynaecol. 2021 Jun;73:125-136. doi: 10.1016/j.bpobgyn.2021.03.004. Epub 2021 Mar 18.

Abstract

Pregnant women and neonates are often categorised as being at high risk during the coronavirus disease-2019 (COVID-19) pandemic. Numerous studies have demonstrated that the characteristics of COVID-19 disease in pregnant women and non-pregnant women are very similar. However, pregnant women with COVID-19 in the third trimester are more likely than their non-pregnant counterparts to require intensive care, though this may reflect a lower threshold for intervention in pregnant women rather than more serious disease. Compared with pregnant women without COVID-19, pregnant women with symptomatic COVID-19 requiring admission to hospital have worse maternal outcomes, including death, although the absolute risk remains very low. Outcomes of neonates born to women positive for COVID-19 are generally very good, though iatrogenic preterm birth is more common. Findings from these studies highlight the need for further monitoring of the outcomes of pregnant and post-partum women according to trimester during this pandemic.

Keywords: COVID-19; ICU admission; Maternal outcomes; Mortality; Neonatal outcomes.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Female
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical
  • Pandemics
  • Pregnancy
  • Pregnancy Complications, Infectious* / epidemiology
  • Pregnancy Outcome / epidemiology
  • Premature Birth* / epidemiology
  • SARS-CoV-2