Progress in electroorganic synthesis is linked to innovation of new synthetic reactions with impact on medicinal chemistry and drug discovery and to the desire to minimise waste and to provide energy-efficient chemical transformations for future industrial processes. Paired electrosynthetic processes that combine the use of both anode and cathode (convergent or divergent) with minimal (or without) intentionally added electrolyte or need for additional reagents are of growing interest. In this overview, recent progress in developing paired electrolytic reactions is surveyed. The discussion focuses on electrosynthesis technology with proven synthetic value for the preparation of small molecules. Reactor types are contrasted and the concept of translating light-energy driven photoredox reactions into paired electrolytic reactions is highlighted as a newly emerging trend.
Keywords: atom economy; diffusion and reaction layer; electrification; electroorganic synthesis; energy conversion.
© 2021 The Authors. Published by The Chemical Society of Japan & Wiley-VCH GmbH.