Repetitive Thoughts and Repetitive Behaviors in Williams Syndrome

J Autism Dev Disord. 2022 Feb;52(2):852-862. doi: 10.1007/s10803-021-04979-w. Epub 2021 Apr 10.


The purpose of the study was to characterize repetitive phenomena in Williams syndrome (WS). The parents of 60 subjects with WS completed the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) or Children's Y-BOCS, the Yale Global Tic Severity Scale, the Stereotyped Behavior Scale, and the Spence Children's Anxiety Scale-Parent Version. Nineteen males and 41 females participated in the study. Six subjects (10%) had obsessions only, six (10%) had compulsions only, and eleven (18%) had at least one obsession and at least one compulsion. None of the subjects had tics. Fifty subjects (83.3%) endorsed at least one stereotypy. Increased anxiety was associated with increased severity of obsessions, but not severity of compulsions or stereotypies.

Keywords: Compulsion; Obsession; Repetitive; Stereotypy; Tic; Williams syndrome.

MeSH terms

  • Autism Spectrum Disorder*
  • Child
  • Female
  • Humans
  • Male
  • Obsessive Behavior / diagnosis
  • Obsessive-Compulsive Disorder* / diagnosis
  • Obsessive-Compulsive Disorder* / epidemiology
  • Psychiatric Status Rating Scales
  • Severity of Illness Index
  • Tics*
  • Williams Syndrome*