One hundred and sixteen patients aged from 65 to 80 years (first group including 39 previously cholecystectomized patients) and 161 patients aged over 80 years (second group, including 31 previously cholecystectomized patients) underwent endoscopic papillotomy for choledocholithiasis. We compared clinical, biochemical and morphological features of choledocolithiasis with early results of endoscopic papillotomy. Clinical symptoms were not different between the old and very old patients, cholecystectomized or not. Charcot's triade was observed in one third of patients. Biochemical data just before endoscopic retrograde cholangiography were not different according to groups: 21 p. 100 of the 277 patients had a biological cholestasis without elevation of bilirubin and 10 p. 100 of the patients had no abnormality of the liver function. Diagnosis of choledocholithiasis was accurately suspected in 90 p. 100 of patients. Complete removal of gallstones after endoscopic papillotomy was obtained in 95 p. 100 of patients in the first group and 93 p. 100 of patients in the second group. Morbidity and mortality rates related to endoscopic papillotomy were not different between the 2 groups (6.9 and 0.8 p. 100 in the first group and 8.7 and 3.1 p. 100 in the second group, the first group and 8.7 and 3.1 p. 100 in the second group, respectively). These results suggest that clinical and biochemical features of choledocholithiasis, and early results of endoscopic treatment do not present any particularities in the elderly.