A review of different resuscitation platforms during delayed cord clamping

J Perinatol. 2021 Jul;41(7):1540-1548. doi: 10.1038/s41372-021-01052-3. Epub 2021 Apr 13.


There is a large body of evidence demonstrating that delaying clamping of the umbilical cord provides benefits for term and preterm infants. These benefits include reductions in mortality in preterm infants and improved developmental scores at 4 years of age in term infants. However, non-breathing or non-vigorous infants at birth are excluded due to the perceived need for immediate resuscitation. Recent studies have demonstrated early physiological benefits in both human and animal models if resuscitation is performed with an intact cord, but this is still an active area of research. Given the large number of ongoing and planned trials, we have brought together an international group that have been intimately involved in the development or use of resuscitation equipment designed to be used while the cord is still intact. In this review, we will present the benefits and limitations of devices that have been developed or are in use. Published trials or ongoing studies using their respective devices will also be reviewed.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Constriction
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Resuscitation
  • Time Factors
  • Umbilical Cord*