Genome Sequences of Three SARS-CoV-2 ORF7a Deletion Variants Obtained from Patients in Hong Kong

Herman Tse; Sally Cheuk-Ying Wong; Ka-Fai Ip; Vincent Chi-Chung Cheng; Kelvin Kai-Wang To; David Christopher Lung; Garnet Kwan-Yue Choi

doi:10.1128/MRA.00251-21

Genome Sequences of Three SARS-CoV-2 ORF7a Deletion Variants Obtained from Patients in Hong Kong

Microbiol Resour Announc. 2021 Apr 15;10(15):e00251-21. doi: 10.1128/MRA.00251-21.

Authors

Herman Tse¹, Sally Cheuk-Ying Wong¹, Ka-Fai Ip¹, Vincent Chi-Chung Cheng², Kelvin Kai-Wang To^{3

4}, David Christopher Lung^{5

6}, Garnet Kwan-Yue Choi⁵

Affiliations

¹ Department of Pathology, Hong Kong Children's Hospital, Hong Kong Special Administrative Region, China.
² Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, China.
³ State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
⁴ Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region, China.
⁵ Department of Pathology, Hong Kong Children's Hospital, Hong Kong Special Administrative Region, China lungdc@ha.org.hk cky603@ha.org.hk.
⁶ Department of Pathology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region, China.

Abstract

We report the genome sequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains from the clinical samples of three coronavirus disease 2019 (COVID-19) patients in Hong Kong. All the genome sequences showed a 370-nucleotide deletion resulting in the complete loss of ORF7a.