Active and realistic passive marijuana exposure tested by three immunoassays and GC/MS in urine

J Anal Toxicol. 1988 May-Jun;12(3):113-6. doi: 10.1093/jat/12.3.113.


Human urine samples obtained before and after active and passive exposure to marijuana were analyzed by immune kits (Roche, Amersham, and Syva) and gas chromatography/mass spectrometry (GC/MS). Seven of eight subjects were positive for the entire five-day test period with one immune kit. The latter correlated with GC/MS in 98% of the samples. Passive inhalation experiments under conditions likely to reflect realistic exposure resulted consistently in less than 10 ng/mL of cannabinoids. The 10-100-ng/mL cannabinoid concentration range essential for detection of occasional and moderate marijuana users is thus unaffected by realistic passive inhalation.

MeSH terms

  • Adult
  • Air Pollutants / analysis*
  • Cannabinoids / urine*
  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Male
  • Marijuana Smoking*
  • Radioimmunoassay


  • Air Pollutants
  • Cannabinoids