Individual risk management strategy for SARS-CoV-2 infection: A step toward personalized healthcare

Int Immunopharmacol. 2021 Jul:96:107629. doi: 10.1016/j.intimp.2021.107629. Epub 2021 Apr 1.


Lethal or critical COVID-19 occurs most in infected hosts with certain risk factors such as advanced age or pre-existing disease. Host metabolic status significantly affects the clinical presentations of SARS-CoV-2 infection. Individual risk management is thus crucial for preventing severe COVID-19. Such susceptibility is individual, depending on a multitude of factors. Personalized risk assessment requires the inclusive analysis of big health data to stratify individual risk and derive a customized action plan. Personalized medicine requires shifting from the virology aspect per se to the whole individual's consideration, including dietary pattern, nutritional status, supporting lifestyle, co-existing diseases, and environmental factors. In this short communication, we discuss the individual management strategy for SARS-CoV2 infection as a step towards future personalized healthcare.

Keywords: COVID-19; Immunomodulation; Nutrient deficiencies; Nutritional supplementation; Personalized medicine; SARs-CoV-2.

MeSH terms

  • COVID-19*
  • Comorbidity
  • Humans
  • Life Style
  • Nutritional Status
  • Precision Medicine*
  • Risk Assessment / methods
  • Risk Factors
  • SARS-CoV-2