Progress of Gastric Cancer Surgery in the era of Precision Medicine

Int J Biol Sci. 2021 Mar 2;17(4):1041-1049. doi: 10.7150/ijbs.56735. eCollection 2021.

Abstract

With the development of genomics, the update of modern imaging technology and the advent of artificial intelligence and big data, the surgical treatment of gastric cancer has gradually stepped into precision medicine. Precision surgery treatment of gastric cancer is based on accurate molecular typing and staging using modern molecular diagnostic technology and imaging, and the formulation of precise and individualized surgical treatment plans, with the concept of minimally invasive and accelerated rehabilitation surgery running through it. For intermediate-stage gastric cancer, we have adopted a comprehensive treatment approach including traditional radiotherapy and chemotherapy, targeted therapy and immunotherapy. Utilize artificial intelligence and big data technology to improve the standardization and interconnectivity of specialty data and realize the transformation of evidence-based medicine. Promoting the standardization, standardization and individualization of gastric cancer surgical treatment, providing patients with precise diagnosis and treatment, and further improving patients' prognosis are the opportunities and challenges in the development of gastric cancer surgery.

Keywords: chemotherapy; gastric cancer; immunotherapy; precision medicine; surgery.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Gastrectomy
  • Humans
  • Neoadjuvant Therapy*
  • Precision Medicine*
  • Stomach Neoplasms / classification
  • Stomach Neoplasms / surgery*