Congenital sensorineural deafness in Dogo Argentino dogs: Prevalence and phenotype associations

Vet Rec. 2021 May;188(9):e299. doi: 10.1002/vetr.299. Epub 2021 Apr 19.

Abstract

Background: The Dogo Argentino dog breed is affected by hereditary congenital sensorineural deafness (CSD) associated with white pigmentation, but prevalence data and associations with phenotypes have not been reported.

Methods: In a retrospective study, animals were tested by the brainstem auditory evoked response, and phenotype data of sex, iris color, patch presence/absence and parent hearing status were collected. Chi-square analyses were performed to identify associations between deafness and phenotype traits.

Results: BAER results and phenotype data were collected for 811 dogs. Hearing status was 74.23% bilaterally hearing, 20.35% unilaterally deaf and 5.43% bilaterally deaf or an overall prevalence of 25.77%. CSD was not associated with sex, but dogs without a patch had a significantly higher prevalence rate than patched dogs. Blue-eyed dogs had higher prevalence rates than brown-eyed dogs, but because of small sample size the χ2 association was not considered valid. Insufficient numbers of dogs with a unilaterally deaf parent were present to assess the effects of parent hearing status.

Conclusion: Approximately one fourth of a US Dogo Argentino population was deaf in one or both ears, but dogs with a patch had a lower prevalence. Dogs with a blue eye were more likely to be deaf, but the association significance could not be reliably assessed.

MeSH terms

  • Animals
  • Dog Diseases / congenital*
  • Dog Diseases / epidemiology
  • Dog Diseases / genetics
  • Dogs
  • Evoked Potentials, Auditory, Brain Stem
  • Female
  • Hearing Loss, Sensorineural / congenital
  • Hearing Loss, Sensorineural / epidemiology
  • Hearing Loss, Sensorineural / genetics
  • Hearing Loss, Sensorineural / veterinary*
  • Male
  • Phenotype
  • Prevalence
  • Retrospective Studies