Anthocyanin supplement as a dietary strategy in cancer prevention and management: A comprehensive review

Crit Rev Food Sci Nutr. 2022;62(26):7242-7254. doi: 10.1080/10408398.2021.1913092. Epub 2021 Apr 19.


Anthocyanins are natural pigments proven to be beneficial in the vast majority of health problems with no side effects. In this review, the latest progress on the cancer prevention and management of anthocyanins in treating cancers ranked in the top 5 of incidence and mortality was summarized, and the interaction and corresponding mechanisms were established based on a systematic review of electronic libraries. Several studies have revealed that anthocyanins have positive impact on human health with anti-cancer capacity. This review aimed to accumulate the evidence on the anti-cancer effects of anthocyanins, corresponding mechanisms and limitation of anthocyanins on cancer prevention and management. Notably, this review updated the latest studies on cancer prevention and management of anthocyanins and also inputted the future perspectives and the demanding questions for the possible contribution of anthocyanins as anti-cancer adjuvant.

Keywords: Anthocyanin; anti-cancer; chemotherapy; immunotherapy.

Publication types

  • Systematic Review

MeSH terms

  • Anthocyanins* / pharmacology
  • Diet
  • Dietary Supplements
  • Humans
  • Neoplasms* / prevention & control


  • Anthocyanins