COVID-19 vaccine acceptance in pregnant women

Int J Gynaecol Obstet. 2021 Aug;154(2):291-296. doi: 10.1002/ijgo.13713. Epub 2021 May 1.


Objective: To determine vaccine acceptance and hesitancy attitudes toward coronavirus disease 2019 (COVID-19) vaccines in pregnant women.

Methods: Three hundred pregnant women were surveyed face to face with 40 questions. Sociodemographic characteristics, vaccination history, perception of risk for the COVID-19 pandemic, the impact of the COVID-19 pandemic, and acceptance of and attitude toward future COVID-19 vaccination were prospectively evaluated.

Results: Among all participants, 111 (37%) stated their intent to receive the vaccine if it were recommended for pregnant women. Most common refusal reasons were lack of data about COVID-19 vaccine safety in pregnant populations and possibility of harm to the fetus. There was a weak positive correlation between COVID-19 vaccine acceptancy and number of school-age children. Pregnant women in the first trimester expressed higher acceptance of COVID-19 vaccination than those in the second and third trimesters.

Conclusion: The present study reported low acceptance of COVID-19 vaccination in a sample of pregnant women. Concern about vaccine safety was the major reason for hesitancy. Identifying attitudes among priority groups will be useful for creating vaccination strategies that increase uptake during the current pandemic.

Keywords: COVID-19; acceptance; hesitancy; pregnant women; severe acute respiratory syndrome coronavirus 2; vaccine.

MeSH terms

  • Adult
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines*
  • Cross-Sectional Studies
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Pandemics / prevention & control
  • Patient Acceptance of Health Care / psychology*
  • Pregnancy
  • Pregnant Women / psychology*
  • SARS-CoV-2
  • Surveys and Questionnaires
  • Vaccination / psychology*


  • COVID-19 Vaccines