Thrombectomy Using the EmboTrap II Device in Late Treatment Patients in the Real-World Setting

World Neurosurg. 2021 Jul:151:e387-e394. doi: 10.1016/j.wneu.2021.04.040. Epub 2021 Apr 18.


Objective: We aimed to evaluate the safety and efficacy of endovascular thrombectomy (EVT) using the EmboTrap Revascularization Device (EmboTrap) in patients with ischemic stroke treated >6-24 hours after stroke onset.

Methods: We performed a retrospective analysis of data from a prospective registry of consecutive patients with stroke with anterior circulation large vessel occlusion treated by stent-retriever thrombectomy with EmboTrap II in a single stroke center in France from 2016 to 2017. Patients were divided into late treatment window (>6-24 hours after stroke onset) or early treatment window (≤6 hours) groups. Baseline clinical and imaging characteristics, rates of successful recanalization (modified Thrombolysis in Cerebral Infarction score ≥2b), complications, 3 months good functional outcome (modified Rankin Scale score 0-2), and mortality were analyzed.

Results: Of the 225 patients (mean age, 71.5 ± 14.5 years; 55.6% [125/225] female) included in the study, 54 were treated in the late treatment window, with a mean time from last known well to treatment of 651 ± 223 minutes. Compared with the early treatment window group, there were no significant differences in baseline characteristics, successful recanalization (83.3% [45/54] vs. 81.3% [139/171]; P = 0.734), 3 months good functional outcome (37.0% [20/54] vs. 37.4% [64/171]; P = 0.959), or mortality (24.1% [13/54] vs. 27.5% [47/171]; P = 0.621).

Conclusions: This real-world study provides evidence that EVT using EmboTrap is safe and effective in the late treatment window in patients with large vessel occlusion.

Keywords: Acute ischemic stroke; EmboTrap; Mechanical thrombectomy; Revascularization.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cerebral Revascularization / instrumentation
  • Cerebral Revascularization / methods
  • Endovascular Procedures / instrumentation
  • Endovascular Procedures / methods
  • Female
  • Humans
  • Ischemic Stroke / surgery*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Thrombectomy / instrumentation*
  • Thrombectomy / methods*
  • Time-to-Treatment*
  • Treatment Outcome