Rare Pulmonary Tumors and Carcinoma Mimickers; Experience from an Interventional Radiology Unit with Radiologic-pathologic Correlation- A Pictoral Essay

Curr Med Imaging. 2021;17(10):1183-1190. doi: 10.2174/1573405617666210420105624.

Abstract

Background: Although imaging findings along with patients' clinical history may give a clue for the etiology of a pulmonary lesion, the differentiation of benign pulmonary lesions from lung cancer could be challenging.

Objective: The aim of this review article was to increase the awareness of carcinoma mimicking lung lesions.

Methods: This paper was designed to illustrate rare pulmonary tumors and carcinoma mimickers with emphasis on radiologic-pathologic correlation. Pitfalls encountered on CT images and also false positivity of PET-CT scans were also presented.

Conclusion: Several benign pulmonary lesions may grow in size on follow-up and some may show pathologic FDG (18F-fluorodeoxyglucose) uptake, which makes them indistinguishable from lung carcinoma by imaging. In addition, some slow-growing malignant lesions, such as carcinoid, may be false-negative on PET/CT scans.

Keywords: CT; Lung cancer; MRI; PET/CT scan.; benign pulmonary tumors; percutaneous transthoracic biopsy.

Publication types

  • Review

MeSH terms

  • Carcinoid Tumor*
  • Fluorodeoxyglucose F18
  • Humans
  • Lung Neoplasms* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Radiology, Interventional
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18