The modulation of contraction of fibroblast populated collagen lattices by types I, II, and III collagen

Tissue Cell. 1988;20(1):47-50. doi: 10.1016/0040-8166(88)90006-7.

Abstract

Human dermal fibroblasts incorporated in a polymerized collagen lattice reduce the size of that matrix. When cell number, collagen concentration, and medium are identical, lattices made with type III collagen contract faster and to a greater degree than those made with type I collagen. The latter contract faster and to a greater degree than those made with type II collagen.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Collagen / physiology*
  • Contractile Proteins / physiology*
  • Fibroblasts / cytology
  • Fibroblasts / physiology
  • Humans
  • Polymers*
  • Skin / cytology
  • Skin Physiological Phenomena*

Substances

  • Contractile Proteins
  • Polymers
  • Collagen