Applying the adverse outcome pathway concept to questions in anaesthetic neurotoxicity

Br J Anaesth. 2021 Jun;126(6):1097-1102. doi: 10.1016/j.bja.2021.03.009. Epub 2021 Apr 20.

¹ Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK; The University of Sheffield, Sheffield, UK. Electronic address: J.waspe@sheffield.ac.uk.
² Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK.
³ Department of Anaesthesia and Intensive Care, University Hospital Odense, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

No abstract available

Keywords: GABA(A) receptor; NMDA receptor; adverse outcome pathway; general anaesthesia; neurotoxicity.

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