Future vaccines in pregnancy

Best Pract Res Clin Obstet Gynaecol. 2021 Oct:76:96-106. doi: 10.1016/j.bpobgyn.2021.03.009. Epub 2021 Mar 24.

Abstract

Vaccination in pregnancy provides an important opportunity to target illnesses that are known to impact pregnant women, fetal development, and newborns in particular. The ability to create antibodies through safe vaccination that cross the placenta can provide protection against maternal, congenital, and newborn infections. At present, multiple vaccines are being developed which have direct benefits for pregnant women and their newborns. Group B streptococcus, Respiratory Syncytial Virus, Cytomegalovirus, Zika, Ebola, Malaria, and Coronavirus SARS-CoV-2 are all being researched with the view to develop a safe vaccine available for pregnant women. There is also an increased movement towards the inclusion of pregnant women in vaccine development and trials - challenging the historical, ethical, and medicolegal arguments against their involvement in such research.

Keywords: Future vaccinations pregnancy.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Female
  • Humans
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Complications, Infectious* / prevention & control
  • SARS-CoV-2
  • Streptococcus agalactiae
  • Vaccination
  • Vaccines*
  • Zika Virus Infection* / prevention & control
  • Zika Virus*

Substances

  • Vaccines