Histologic diagnosis of extrinsic allergic alveolitis

Am J Surg Pathol. 1988 Jul;12(7):514-8. doi: 10.1097/00000478-198807000-00002.


Twenty-seven patients with open-lung biopsy findings consistent with extrinsic allergic alveolitis (hypersensitivity pneumonitis) were studied. In only one case had the diagnosis been considered prior to the biopsy. Among the 27 patients, a causative exposure was subsequently identified in 10, and no apparent cause could be found in the remaining 17. The prognosis for the entire group was good; all 10 patients in whom an exposure was found and 13 of 17 without causative exposure are alive without progressive lung disease.

MeSH terms

  • Alveolitis, Extrinsic Allergic / pathology*
  • Biopsy
  • Humans
  • Lung / pathology
  • Radiography, Thoracic
  • Respiratory Function Tests