The Surgical Treatment of Pyogenic Spondylodiscitis using Carbon-Fiber-Reinforced Polyether Ether Ketone Implants: Personal Experience of a Series of 81 Consecutive Patients

World Neurosurg. 2021 Jul:151:e495-e506. doi: 10.1016/j.wneu.2021.04.064. Epub 2021 Apr 24.

Abstract

Background: Pyogenic spondylodiscitis (PSD) is a complex disorder that often required postoperative imaging. Carbon-fiber-reinforced polyether ether ketone (CFRP) is radiolucent and offers an optimal assessability of anatomic structures.

Methods: A retrospective file review of patients who were operated on for PSD using CFRP implants was performed to assess the clinical outcome, implant-associated complications, and revision surgery. A minimum follow-up of 3 months was required for evaluation of clinical and radiographic data, which included computed tomography and magnetic resonance imaging (MRI) assessment, to determine implant stability and assessability of soft tissue and nerve structures using a grading system.

Results: Eighty-one consecutive patients with a mean of 69.5 years were identified. Debridement and stabilization were performed in 8 cervical, 17 thoracic, and 57 lumbar procedures; 72 interbody fusion procedures using cages were performed. Intraoperatively, no implant-associated complication was noted. The mean follow-up was 7 months, at which 52 patients attended. Improved mobility and reduced pain levels were reported by 87%, and MRI assessability was graded ideal. Residual sign of infection was seen in 5 cases, which influenced antibiotic therapy. Asymptomatic radiolucent zones were identified in 13 patients (16%) and screw loosening in 2 (2.4%). In 1 patient, the pedicle screw tip broke and remained within the vertebral body. A repeated procedure because of progressive vertebral body destruction, implant loosening, or subsidence was performed in 5 patients (6.1%).

Conclusions: The surgical treatment of PSD using CFRP is safe. The repeat procedure rate as a result of implant loosening is 6.1%. Minimal artifacts offer ideal assessability of soft tissue structures on an MRI.

Keywords: CT scan; Carbon-fiber–reinforced PEEK; Clinical outcome; Infection; MRI scan; Pyogenic spondylodiscitis; Radiolucent zone.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Benzophenones
  • Carbon Fiber
  • Discitis / surgery*
  • Female
  • Humans
  • Lumbar Vertebrae
  • Lumbosacral Region
  • Male
  • Middle Aged
  • Polymers
  • Prostheses and Implants*
  • Retrospective Studies
  • Spinal Fusion / instrumentation*
  • Thoracic Vertebrae
  • Treatment Outcome

Substances

  • Benzophenones
  • Carbon Fiber
  • Polymers
  • polyetheretherketone