Potential culprits for immediate hypersensitivity reactions to BNT162b2 mRNA COVID-19 vaccine: not just PEG

Eur Ann Allergy Clin Immunol. 2021 Sep;53(5):240-242. doi: 10.23822/EurAnnACI.1764-1489.214. Epub 2021 Apr 29.

Authors

A Radice¹, F Fassio¹, E Meucci¹, M C L Iorno¹, D Macchia¹

Affiliation

¹ Unit of Allergy and Clinical Immunology, San Giovanni di Dio Hospital, Azienda USL Toscana Centro, Florence, Italy.

PMID: 33913314
DOI: 10.23822/EurAnnACI.1764-1489.214

No abstract available

Keywords: Allergic reactions; hypersensitivity; lipid nanoparticles; mRNA COVID-19 vaccine; polyethylene glycols.

Publication types

Letter

MeSH terms

Acetamides / adverse effects*
Amino Alcohols / adverse effects*
BNT162 Vaccine
COVID-19 Vaccines / adverse effects*
COVID-19 Vaccines / chemistry
Decanoates / adverse effects*
Drug Compounding
Drug Hypersensitivity / etiology*
Drug Hypersensitivity / immunology
Fatty Alcohols / adverse effects*
Humans
Hypersensitivity, Immediate / chemically induced*
Hypersensitivity, Immediate / immunology
Nanoparticles
Polyethylene Glycols / adverse effects*
Risk Assessment
Risk Factors

Substances

Acetamides
Amino Alcohols
COVID-19 Vaccines
Decanoates
Fatty Alcohols
Polyethylene Glycols
(4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)
BNT162 Vaccine
2-((polyethylene glycol)-2000)-N,N-ditetradecylacetamide