Short Communication: Coronavirus Disease 19 Among People Living with HIV in Western India: An Observational Cohort Study

AIDS Res Hum Retroviruses. 2021 Aug;37(8):620-623. doi: 10.1089/AID.2021.0004. Epub 2021 May 31.

Abstract

A retrospective cohort study was conducted to assess clinical characteristics and outcomes of coronavirus disease-19 (COVID-19) among people living with HIV (PLHIV) in western India. Out of 86 PLHIV with COVID-19 illness, 19.7% had severe/critical illness and 6 (6.9%) individuals died. Median (interquartile range) age was 51 (47-56) years and 77.6% were male. Eighty-five PLHIV were on antiretroviral treatment with 98% having a viral load <200 copies/mL. Hypertension (HTN) (38.3%) and diabetes mellitus (17.4%) were commonest comorbidities. Fifty-eight percent PLHIV were hospitalized while 6.9% individuals needed intensive care. Presence of medical comorbidity was significantly associated with severe/critical COVID-19, whereas HTN was significantly associated with mortality. Recovery from COVID-19 was documented in 93% PLHIV. In conclusion, PLHIV in western India have similar COVID-19 clinical outcomes as compared with those reported historically among general population. Presence of medical comorbidities rather than HIV-related disease characteristics is associated with severe COVID-19 illness.

Keywords: COVID-19; India; PLHIV; comorbidities.

MeSH terms

  • COVID-19 / diagnosis
  • COVID-19 / epidemiology*
  • Comorbidity
  • Female
  • HIV Infections / epidemiology*
  • Humans
  • India / epidemiology
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • SARS-CoV-2