Biological Properties and Prospects for the Application of Eugenol-A Review

Int J Mol Sci. 2021 Apr 1;22(7):3671. doi: 10.3390/ijms22073671.

Abstract

Eugenol is a phenolic aromatic compound obtained mainly from clove oil. Due to its known antibacterial, antiviral, antifungal, anticancer, anti-inflammatory and antioxidant properties, it has long been used in various areas, such as cosmetology, medicine, and pharmacology. However, high concentrations can be toxic. A dose of 2.5 mg/kg body weight is regarded as safe. This paper reviews the current state of knowledge regarding the activities and application of eugenol and its derivatives and recent research of these compounds. This review is based on information concerning eugenol characteristics and recent research from articles in PubMed. Eugenol remains of great interest to researchers, since its multidirectional action allows it to be a potential component of drugs and other products with therapeutic potential against a range of diseases.

Keywords: antibacterial; antifungal; antioxidant; clove oil; eugenol.

Publication types

  • Review

MeSH terms

  • Analgesics / pharmacology
  • Animals
  • Anti-Infective Agents / pharmacology
  • Anti-Inflammatory Agents / pharmacology
  • Antineoplastic Agents / pharmacology
  • Antioxidants / pharmacology
  • Eugenol / analogs & derivatives
  • Eugenol / pharmacology*
  • Eugenol / therapeutic use
  • Humans

Substances

  • Analgesics
  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Antioxidants
  • Eugenol