The Impact of Temporary Stay at High Altitude on the Circulatory System

J Clin Med. 2021 Apr 12;10(8):1622. doi: 10.3390/jcm10081622.


In recent times many people stay temporarily at high altitudes. It is mainly associated with the growing popularity of regular air travel, as well as temporary trips to mountain regions. Variable environmental conditions, including pressure and temperature changes, have an impact on the human body. This paper analyses the physiological changes that may occur while staying at high altitude in healthy people and in people with cardiovascular diseases, such as arterial hypertension, pulmonary hypertension, heart failure, ischemic heart disease, or arrhythmias. Possible unfavourable changes were underlined. Currently recognized treatment recommendations or possible treatment modifications for patients planning to stay at high altitudes were also discussed.

Keywords: circulatory system; environmental health; high altitude.

Publication types

  • Review