Analysis of Recent Literature on Lung Volume Reduction Surgery

Daniel P McCarthy; Lauren J Taylor; Malcolm M DeCamp

doi:10.1016/j.thorsurg.2021.01.003

Analysis of Recent Literature on Lung Volume Reduction Surgery

Thorac Surg Clin. 2021 May;31(2):119-128. doi: 10.1016/j.thorsurg.2021.01.003.

Authors

Daniel P McCarthy¹, Lauren J Taylor², Malcolm M DeCamp³

Affiliations

¹ Division of Cardiothoracic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792, USA.
² Division of Cardiothoracic Surgery, University of Colorado, Anschutz Medical Campus, 12631 East 17th Avenue, Room 5401, Mail Stop C-291, Aurora, CO 80045, USA.
³ Division of Cardiothoracic Surgery, Department of Surgery, University of Wisconsin-Madison, 600 Highland Avenue, H4/340, Madison, WI 53792-0001, USA. Electronic address: decamp@surgery.wisc.edu.

PMID: 33926666
DOI: 10.1016/j.thorsurg.2021.01.003

Abstract

Publication of the National Emphysema Treatment Trial (NETT) in 2003 established lung volume reduction surgery (LVRS) as a viable treatment of select patients with moderate to severe emphysema, and the only intervention since the availability of ambulatory supplemental oxygen to improve survival. Despite these findings, surgical treatment has been underused in part because of concern for high morbidity and mortality. This article reviews recent literature generated since the original NETT publication, focusing on physiologic implications of LVRS, recent data regarding the safety and durability of LVRS, and patient selection and extension of NETT criteria to other patient populations.

Keywords: COPD; Emphysema; Lung volume reduction surgery.

Publication types

Review

MeSH terms

Clinical Trials as Topic
Humans
Inflammation / metabolism*
Patient Safety
Patient Selection
Pneumonectomy / methods*
Pulmonary Disease, Chronic Obstructive / surgery*
Pulmonary Emphysema / mortality
Pulmonary Emphysema / surgery*
Pulmonary Medicine / trends
Quality of Life
Risk
Treatment Outcome
United States