Chitin and chitosan as tools to combat COVID-19: A triple approach

Int J Biol Macromol. 2021 Jul 31:183:235-244. doi: 10.1016/j.ijbiomac.2021.04.157. Epub 2021 Apr 27.


The progressive and fatal outbreak of the newly emerged coronavirus, SARS-CoV-2, necessitates rigorous collaboration of all health care systems and researchers from all around the world to bring such a devastating pandemic under control. As there is so far no officially approved drug or ideal vaccine for this disease, investigations on this infectious disease are actively pursued. Chitin and chitosan have shown promising results against viral infections. In this review, we first delve into the problematic consequences of viral pandemics followed by an introduction on SARS-CoV-2 taxonomical classification. Then, we elaborate on the immunology of COVID-19. Common antiviral therapies and their related limitations are described and finally, the potential applicability of chitin and chitosan to fight this overwhelming viral pandemic is addressed.

Keywords: COVID-19; Chitin; Chitosan; SARS-CoV-2.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / therapeutic use*
  • COVID-19 / epidemiology
  • COVID-19 Drug Treatment*
  • Chitin / therapeutic use*
  • Chitosan / therapeutic use*
  • Humans
  • Pandemics*
  • SARS-CoV-2*


  • Antiviral Agents
  • Chitin
  • Chitosan