Spinal cord injury: A multisystem physiological impairment/dysfunction

Rev Neurol (Paris). 2021 May;177(5):594-605. doi: 10.1016/j.neurol.2021.02.385. Epub 2021 Apr 27.

Abstract

Spinal cord injury (SCI) is a complex disease that affects not only sensory and motor pathways below the neurological level of injury (NLI) but also all the organs and systems situated below this NLI. This multisystem impairment implies comprehensive management in dedicated SCI specialized centers, by interdisciplinary and multidisciplinary teams, able to treat not only the neurological impairment, but also all the systems and organs affected. After a brief history of the Spinal Cord Medicine, the author describes how to determine the level and severity of a SCI based on the International Standards for Neurological Classification of Spinal Cord Injury and the prognosis factors of recovery. This article provides also a review of the numerous SCI-related impairments (except for urinary, sexual problems and pain treated separately in this issue), their principles of management and related complications.

Keywords: Lifelong follow-up; Morbidity; Mortality and life expectancy; Multisystem impairment; SCI Centers; SCI – related organ's dysfunctions and complications; Spinal cord injury.

Publication types

  • Review

MeSH terms

  • Humans
  • Spinal Cord Injuries*