Lifting effect of onabotulinumtoxinA in patients treated for glabellar and crow's feet rhytids

J Cosmet Laser Ther. 2020 Nov 16;22(6-8):232-238. doi: 10.1080/14764172.2021.1918341. Epub 2021 May 4.

Abstract

OnabotulinumtoxinA injection can enhance the appearance of the eyes. This study evaluated the lifting effect of onabotulinumtoxinA treatment of the eye area. A retrospective, single-center audit of patients treated for glabellar and crow's feet rhytids was undertaken. Standardized photographs taken before and 2-4 weeks after treatment were assessed. Computer-based measurements were made of the height of the visible superior tarsal plate (STP) and brow (measured from upper eyelid lash edge to eyebrow base) at rest and maximum frown. One hundred patients were included (96 females; mean age: 46.2 ± 8.8 years). Mean onabotulinumtoxinA doses were 14.95 ± 0.61 units (glabella) and 17.83 ± 2.74 units (crow's feet). There were significant post-treatment increases in mean STP height at rest (left side, 0.76 ± 0.99 mm, p = .02; right side, 0.79 ± 0.94 mm, p = .01) and maximum frown (left, 2.25 ± 1.52 mm, p < .0001; right, 1.87 ± 1.34 mm, p < .0001), and mean brow height at rest (left side, 1.54 ± 1.49 mm, p = .0006; right side, 1.47 ± 1.84 mm, p = .0009) and maximum frown (left, 4.37 ± 2.29 mm, p < .0001; right, 4.16 ± 1.88 mm, p < .0001). OnabotulinumtoxinA injection is effective for elevating brow position and increasing STP show.

Keywords: Superior tarsal plate; crow’s feet; glabella; onabotulinumtoxinA; rhytids.

MeSH terms

  • Adult
  • Botulinum Toxins, Type A* / therapeutic use
  • Cosmetic Techniques*
  • Female
  • Humans
  • Lifting
  • Middle Aged
  • Neuromuscular Agents* / therapeutic use
  • Retrospective Studies
  • Skin Aging*

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A