Is complement the culprit behind COVID-19 vaccine-related adverse reactions?

J Clin Invest. 2021 Jun 1;131(11):e151092. doi: 10.1172/JCI151092.

Authors

Dimitrios C Mastellos¹, Panagiotis Skendros², John D Lambris³

Affiliations

¹ National Center for Scientific Research 'Demokritos', Athens, Greece.
² First Department of Internal Medicine and Laboratory of Molecular Hematology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece.
³ Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

No abstract available

Publication types

Review

MeSH terms

COVID-19 / immunology*
COVID-19 / prevention & control
COVID-19 Vaccines / adverse effects*
COVID-19 Vaccines / immunology
COVID-19 Vaccines / therapeutic use
Complement Activation / drug effects*
Complement Activation / immunology
Complement System Proteins / immunology*
Humans
SARS-CoV-2 / immunology*

Substances

COVID-19 Vaccines
Complement System Proteins