Modeling myelin: A toolkit for exploring myelin's mysteries in vitro

Dev Cell. 2021 May 3;56(9):1215-1217. doi: 10.1016/j.devcel.2021.04.015.


In the myelin field, there is a lack of reliable in vitro tools to study myelination, especially using human cells. In this issue of Developmental Cell, James et al. present a guide to generating human iPSC-derived "myelinoids"-3D models of myelination that reliably achieve mature myelin formation.

Publication types

  • Comment

MeSH terms

  • Humans
  • Induced Pluripotent Stem Cells*
  • Myelin Sheath*