Ocular Syphilis in Patients With Human Immunodeficiency Virus Infection

Am J Ophthalmol. 1988 Jul 15;106(1):1-6. doi: 10.1016/s0002-9394(14)76378-0.

Abstract

We diagnosed ocular syphilis in three homosexual men infected with human immunodeficiency virus (HIV). Ocular inflammation included uveitis, optic neuritis, and retinitis. Dermatologic and central nervous system manifestations of secondary syphilis were also present. The history of homosexuality was difficult to obtain. Concomitant infection with HIV may alter the course of syphilis, obscure the diagnosis, and impair the response to therapy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Eye Diseases / complications*
  • Eye Diseases / drug therapy
  • Eye Diseases / physiopathology
  • Fundus Oculi
  • Humans
  • Male
  • Retinal Diseases / drug therapy
  • Retinal Diseases / etiology
  • Steroids / therapeutic use
  • Syphilis / complications*
  • Syphilis / drug therapy
  • Syphilis / physiopathology
  • Syphilis, Cutaneous / complications
  • Syphilis, Cutaneous / pathology
  • Uveitis / drug therapy
  • Uveitis / etiology
  • Visual Fields

Substances

  • Anti-Bacterial Agents
  • Steroids