Adult Pilocytic Astrocytoma in the insula: Case report and review of the literature

Ann Med Surg (Lond). 2021 Apr 15:65:102300. doi: 10.1016/j.amsu.2021.102300. eCollection 2021 May.

Abstract

Introduction: and Importance: Adult Pilocytic Astrocytomas (APA) are infrequent low grade tumors. While supratentorial APA is considered rare, insular APA is extremely rare.

Case presentation: We present a case of pure insular APA along with surgical outcomes. Tractography and functional MRI were obtained pre-operatively. The patient underwent neuro-navigation guided microsurgical resection with sub-cortical white matter mapping, utilizing Intra-operative MRI guidance. The Sylvain fissure was opened to secure the M3 branches, and near total resection was achieved.

Clinical discussion: APA in the insula is a very rare presentation and is considered challenging. Its proximity to the middle cerebral and lenticulostriate arteries, motor areas, and language areas makes accessing and resecting the tumor challenging. A multidisciplinary approach by an experienced team is needed to plan the management of young adult patients and reach the best outcomes.

Conclusion: Implementing microsurgical techniques, modern imaging modalities and intraoperative mapping helps to achieve maximal safe resection without risking functions.

Keywords: Adult; Insular; KPS, Karnofsky scale; LSA, lenticulostriate arteries; MCA, middle cerebral artery; Microsurgery; Outcomes; Pilocytic Astrocytoma.

Publication types

  • Case Reports