Sexual function in patients with idiopathic inflammatory myopathies: a cross-sectional study

Rheumatology (Oxford). 2021 Nov 3;60(11):5060-5072. doi: 10.1093/rheumatology/keab397.

Abstract

Objectives: To date, there is almost no information concerning the sexual health of patients with idiopathic inflammatory myopathies (IIM). This cross-sectional study aimed to compare sexual function in patients with IIM to age-/sex-matched healthy controls (HC) and determine the potential impact of clinical features on sexual function.

Methods: In total, 122 women (61 with IIM, 61 age-matched HC) and 22 men (11 with IIM, 11 age-matched HC) aged 18-80 years completed gender-specific selection of 7 well-established and validated questionnaires assessing sexual health and function (Female Sexual Function Index, Brief Index of Sexual Function for Women, Sexual Function Questionnaire, Sexual Quality of Life Questionnaire-Female, International Index of Erectile Function, Male Sexual Health Questionnaire, Sexual Quality of Life Questionnaire-Male). Results were compared between patients and HC and correlated with selected disease-related features.

Results: The prevalence of sexual dysfunction in IIM was 59% in women (vs 40% in HC), and 64% (vs 9% in HC) in men. Men and women with IIM reported significantly impaired sexual function compared with sex-/age-matched HC. Decreased sexual function was associated with muscle weakness, disability, physical inactivity, fatigue, depression and decreased quality of life.

Conclusions: Our results suggest that sexual dysfunction is common among IIM patients and more attention should be paid to this aspect of the disease.

Keywords: erectile dysfunction; female sexual dysfunction; idiopathic inflammatory myopathies; sexual health.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Case-Control Studies
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myositis / physiopathology*
  • Myositis / psychology
  • Pelvic Floor / physiopathology
  • Sexual Behavior / physiology*
  • Sexual Health*