The neural-network (NN)-based control method is a new emerging promising technique for controller design in a power electronic circuit (PEC). However, the optimization of NN-based controllers (NNCs) has significant challenges in two aspects. The first challenge is that the search space of the NNC optimization problem is such complex that the global optimization ability of the existing algorithms still needs to be improved. The second challenge is that the training process of the NNC parameters is very computationally expensive and requires a long execution time. Thus, in this article, we develop a powerful evolutionary computation-based algorithm to find a high-quality solution and reduce computational time. First, the differential evolution (DE) algorithm is adopted because it is a powerful global optimizer in solving a complex optimization problem. This can help to overcome the premature convergence in local optima to train the NNC parameters well. Second, to reduce the computational time, the DE is extended to distribute DE (DDE) by dispatching all the individuals to different distributed computing resources for parallel computing. Moreover, a resource-aware strategy (RAS) is designed to further efficiently utilize the resources by adaptively dispatching individuals to resources according to the real-time performance of the resources, which can simultaneously concern the computing ability and load state of each resource. Experimental results show that, compared with some other typical evolutionary algorithms, the proposed algorithm can get significantly better solutions within a shorter computational time.