Overcoming translational barriers in modeling macular degenerations

Cell Stem Cell. 2021 May 6;28(5):781-783. doi: 10.1016/j.stem.2021.04.015.


Advances in tissue mimetics are paving the way for interrogating both the pathobiology of human disease and innovative therapeutic paradigms. In this issue of Cell Stem Cell, Manian et al. (2021) develop a novel iPSC-derived retinal pigment epithelium (RPE)-choriocapillaris (CC) complex that recapitulates key features of macular degenerations.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural
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