The future belongs to those who prepare for it today

Soraya Martín-Suárez; Juan Manuel Encinas

doi:10.1016/j.stem.2021.04.014

The future belongs to those who prepare for it today

Cell Stem Cell. 2021 May 6;28(5):783-785. doi: 10.1016/j.stem.2021.04.014.

Authors

Soraya Martín-Suárez¹, Juan Manuel Encinas²

Affiliations

¹ Biocruces Bizkaia Health Research Institute, Cruces Plaza, 48903 Barakaldo, Bizkaia, Spain.
² Achucarro Basque Center for Neuroscience, UPV/EHU, Scientific Park, 48940 Leioa, Bizkaia, Spain; Ikerbasque, The Basque Foundation for Science, Plaza Euskadi, 5, 48009 Bilbao, Bizkaia, Spain; Department of Neurosciences, University of the Basque Country (UPV/EHU), Scientific Park, 48940 Leioa, Bizkaia, Spain. Electronic address: jm.encinas@ikerbasque.org.

PMID: 33961757
DOI: 10.1016/j.stem.2021.04.014

Abstract

Hippocampal neural stem cells (NSCs) and neurogenesis decline sharply with age, though a small population remains. Two articles in this issue of Cell Stem Cell by Ibrayeva et al. (2021) and Harris et al. (2021) indicate the presence of subpopulations of NSCs whose dynamics of activation and self-renewal change over time and may be key to NSC preservation.

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MeSH terms

Adult Stem Cells*
Cell Proliferation
Hippocampus
Neural Stem Cells*
Neurogenesis