The secret to longevity and healthier communities lies in a systems-level lifestyle-based approach. There are currently 5 regions across the world where people live relatively longer, healthier, and happier lives. Taking lessons from these areas, dubbed "blue zones," we can help improve health and wellness at the population level. There are already cases of these Blue Zones Projects implemented in communities across the United States, which have had demonstrable, positive impacts on public health. Collaboration between the public and private sectors at the local level can make these changes to improve lifestyles and reduce the burden of chronic diseases on the healthcare system.