SchistoCyte Atlas: A Single-Cell Transcriptome Resource for Adult Schistosomes

Trends Parasitol. 2021 Jul;37(7):585-587. doi: 10.1016/j.pt.2021.04.010. Epub 2021 May 9.

Abstract

Schistosomes cause untold disease and disability in the developing world. Here, we introduce SchistoCyte Atlas, a web-based platform for exploring gene expression at single-cell resolution in adult Schistosoma mansoni. Similar resources accessible to non-specialists across the globe will expedite our ability to understand the biology of these devastating parasites.

Keywords: RNAi screening; schistosome; single-cell RNAseq; web-based resource.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Helminth Proteins / genetics*
  • Helminth Proteins / metabolism
  • Life Cycle Stages / genetics
  • Schistosoma mansoni / genetics*
  • Schistosoma mansoni / metabolism
  • Transcriptome*

Substances

  • Helminth Proteins