Endomyocardial biopsy in patients with systemic lupus erythematosus

J Rheumatol. 1988 Apr;15(4):593-6.


Systemic lupus erythematosus (SLE) has numerous cardiovascular manifestations. Myocarditis is present in more than 50% of patients with SLE at autopsy, but it may be silent clinically during life. Percutaneous endomyocardial biopsy performed in 4 patients with SLE was found helpful in establishing the diagnosis and in determining the extent of the inflammatory myocarditis. The findings aided the regulation of therapy, particularly the administration of immunosuppressive drugs.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Biopsy
  • Endocardium / pathology*
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / pathology*
  • Middle Aged
  • Myocarditis / drug therapy
  • Myocarditis / etiology
  • Myocarditis / pathology
  • Myocardium / pathology*
  • Prednisone / therapeutic use


  • Immunosuppressive Agents
  • Prednisone