Opportunities and challenges in translational science

Clin Transl Sci. 2021 Sep;14(5):1629-1647. doi: 10.1111/cts.13055. Epub 2021 Jul 8.


The mission of translational science is to bring predictivity and efficiency to the development and dissemination of interventions that improve human health. Ten years ago this year, the National Center for Advancing Translational Sciences was founded to embody, conduct, and support this new discipline. The Center's first decade has brought substantial progress across a broad range of translational areas, from diagnostic and drug development to clinical trials to implementation science to education. The origins of the translational science and advances to this point are reviewed here and allow the establishment of an ambitious future research agenda for the field.

Publication types

  • Historical Article
  • Review

MeSH terms

  • History, 20th Century
  • History, 21st Century
  • Humans
  • National Institutes of Health (U.S.) / history
  • National Institutes of Health (U.S.) / organization & administration
  • Translational Science, Biomedical / history
  • Translational Science, Biomedical / organization & administration
  • Translational Science, Biomedical / trends*
  • United States