Two Cases of Cronobacter Sakazakii Meningitis in Infants: The Importance Of Early Advanced Brain Imaging and Public Health Reporting

Pediatr Infect Dis J. 2021 Sep 1;40(9):e346-e348. doi: 10.1097/INF.0000000000003184.


We report 2 infants hospitalized with Cronobacter sakazakii meningitis. Each infant had exposure to powdered infant formula at home. Both infants survived, but 1 infant had a subdural empyema drained and developed left sensorineural hearing loss. Early advanced brain imaging is recommended in infants with C. sakazakii meningitis. Reporting to state and federal public health officials may help identify outbreaks.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Brain / diagnostic imaging*
  • Brain / microbiology
  • Cronobacter sakazakii / genetics
  • Cronobacter sakazakii / pathogenicity*
  • Disease Outbreaks / prevention & control
  • Enterobacteriaceae Infections / cerebrospinal fluid
  • Enterobacteriaceae Infections / diagnostic imaging*
  • Enterobacteriaceae Infections / drug therapy
  • Female
  • Hospitalization
  • Humans
  • Infant
  • Infant Formula / microbiology*
  • Infant, Newborn
  • Male
  • Meningitis, Bacterial / diagnostic imaging*
  • Public Health*
  • Treatment Outcome


  • Anti-Bacterial Agents