Disparities Among Limited English Proficient Patients in Colon Cancer Screening with Multi-target DNA Stool Test

J Immigr Minor Health. 2022 Apr;24(2):556-559. doi: 10.1007/s10903-021-01214-7. Epub 2021 May 15.


Racial and language minority groups in the U.S. are at a higher risk for morbidity and mortality from colorectal cancer (CRC), partially due to lower screening rates. This is a retrospective cohort study comparing successful multi-target stool DNA test (mt-sDNA) test completion among patients with limited English proficiency (LEP) and English proficient (EP) patients, from 2015 to 2018. Patients with LEP were frequency matched to EP patients by age at a 3:1 ratio. The percentage of mt-sDNA tests without useful results was 53% among patients with LEP compared to 29% among EP patients (p < 0.0001). The median number of days from order placement to test completion was 62.5 among patients with LEP compared to 33 for EP patients (p = 0.003). This study demonstrates a significant disparity in CRC screening completion using the mt-sDNA test among populations with LEP, which may widen existing disparities in CRC mortality.

Keywords: CRC; Cancer screening; Colon cancer; Disparity; Limited English proficiency; Multi-target stool DNA.

MeSH terms

  • Child, Preschool
  • Colonic Neoplasms*
  • Colorectal Neoplasms* / diagnosis
  • DNA
  • Early Detection of Cancer / methods
  • Humans
  • Limited English Proficiency*
  • Mass Screening / methods
  • Retrospective Studies


  • DNA