Prevalence of Post-COVID-19 Cough One Year After SARS-CoV-2 Infection: A Multicenter Study

Lung. 2021 Jun;199(3):249-253. doi: 10.1007/s00408-021-00450-w. Epub 2021 May 16.


This multicenter study presents prevalence data and associated risk factors of post-COVID-19 cough one year after hospital discharge in COVID-19 survivors. Individuals recovered from COVID-19 at three public hospitals in Madrid (Spain) were scheduled for a telephonic interview. They were systematically asked about the presence of respiratory symptoms, e.g., fatigue, dyspnea, chest pain, and cough after hospital discharge. Clinical and hospitalization data were collected from hospital records. Overall, 1,950 patients (47% women, mean age:61, SD:16 years) were assessed at 11.2 months (SD 0.5) after hospital discharge. Just 367 (18.8%) were completely free of any respiratory post-COVID -19 symptom. The prevalence of long-term cough, chest pain, dyspnea, and fatigue was 2.5%, 6.5%, 23.3%, and 61.2%, respectively. Clinical and hospitalization factors were not associated with long-term post-COVID-19 cough. In conclusion, the prevalence of post-COVID-19 cough one year after SARS-CoV-2 infection was 2.5% in subjects who had survived hospitalization for COVID-19. No clear risk factor associated to long-term post-COVID-19 cough was identified.

Keywords: COVID-19; Cough; Persistent; Risk factors; Symptoms.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • COVID-19 / complications*
  • Chest Pain / epidemiology
  • Chest Pain / virology
  • Cough / epidemiology*
  • Cough / virology*
  • Dyspnea / epidemiology
  • Dyspnea / virology
  • Fatigue / epidemiology
  • Fatigue / virology
  • Female
  • Follow-Up Studies
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • SARS-CoV-2
  • Spain / epidemiology
  • Time Factors