Agenesis of the corpus callosum and schizophrenia: a case report

Psychol Med. 1988 May;18(2):341-7. doi: 10.1017/s0033291700007881.


Clinical, radiological and neuropsychological findings in the first reported case of schizophrenia with complete agenesis of the corpus callosum are described. Although causal inferences were made difficult by the co-existence of a left frontotemporal cyst and a family history of affective disorder, some theories of the role of callosal dysfunction in schizophrenia require revision in the light of this case.

Publication types

  • Case Reports

MeSH terms

  • Agenesis of Corpus Callosum*
  • Corpus Callosum / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurocognitive Disorders / pathology*
  • Neuropsychological Tests
  • Schizophrenia / pathology*
  • Schizophrenic Psychology
  • Tomography, X-Ray Computed