Waveguide-based absorption measurement system for visible wavelength applications

Biomed Opt Express. 2021 Mar 15;12(4):2041-2053. doi: 10.1364/BOE.418264. eCollection 2021 Apr 1.

Abstract

We present a miniaturized waveguide-based absorption measurement system operating at a wavelength of 635 nm, based on a silicon nitride integrated photonic platform, suitable for lab-on-chip applications. We experimentally demonstrate a high correlation between the bulk dye concentration and the measured absorption loss levels in the waveguides. We explain a photonic design process for choosing the ideal waveguide to minimize the coefficient of variation on the analyte concentration. The approach is designed for camera readout, allowing multiple readouts and easy integration for lab-on chip cartridge approach.